The parents of Madeleine McCann say reports they have received a letter from German authorities stating that Madeleine is dead are "false".
In a statement, Kate and Gerry McCann said the reports had "caused unnecessary anxiety to friends and family and once again disrupted our lives".
"The widely reported news that we have a received a letter from the German authorities that states there is evidence or proof that Madeleine is dead is FALSE," they wrote.
"As we have stated many times before, we will not give a running commentary on the investigation – that is the job of the law enforcement agencies and we will support them in any way requested."
It had been reported that a German prosecutor had written to the McCanns telling them he has "concrete evidence" that Madeleine is dead.
It was claimed that Hans Christian Wolters had told the parents that he has no doubt their daughter is dead, but he refused to tell them why.
He reportedly told them that to reveal the evidence would jeopardise his investigation into the German suspect known as Christian B.